NCF1 Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA:1:20000. WB:0.5-1.5µg/ml.IHC:5µg/ml
Reactivity	Human, Mouse, Rat, Rabbit, Pig, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-SESTKRKLASAV, from the C Terminus of the protein sequence according to NP_000256.3.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	44.5 kDa
Gene Name	neutrophil cytosolic factor 1
Database Link	NP_000256 Entrez Gene 17969 MouseEntrez Gene 114553 RatEntrez Gene 653361 Human UniProt ID P14598
Background	The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq]
Synonyms	NCF1A; NOXO2; p47phox; SH3PXD1A
Reference Data
Protein Pathways	Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton

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