LINGO1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1:1000, IHC: 1:10~50
Reactivity	Human, Mouse, Chicken, Monkey
Host	Rabbit
Clonality	Polyclonal
Immunogen	This LINGO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-92 amino acids from the N-terminal region of human LINGO1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	lot specific
Purification	This antibody is purified through a protein G column, followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	69876 Da
Gene Name	leucine rich repeat and Ig domain containing 1
Database Link	NP_116197 Entrez Gene 235402 MouseEntrez Gene 714985 MonkeyEntrez Gene 84894 Human UniProt ID Q96FE5
Background	LINGO1 is a functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. It is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.
Synonyms	LERN1; LRRN6A; UNQ201
Reference Data
Protein Families	Druggable Genome, Transmembrane

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