BMAL1 (ARNTL) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ChIP, Simple Western, WB
Recommend Dilution	Western Blot: 1:100 - 1:200, Simple Western: 1:100, Chromatin Immunoprecipitation (ChIP): 1:10-1:500
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Bacterially expressed human BMAL1
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	aryl hydrocarbon receptor nuclear translocator like
Database Link	NP_001169 Entrez Gene 406 Human UniProt ID O00327
Background	MOP3 (BMAL1), a general dimerization partner for a subset of the bHLH-PAS (basic-helix-loop-helix-PER-ARNT-SIM) superfamily of transcription regulators, is involved in circadian rhythm generation. MOP3 interacts with MOP4, CLOCK, Hypoxia-inducible factor-1 alpha and -2 alpha. This interaction appears to be distinct from that of the more characterized general partner, ARNT (HIF-1Beta).
Synonyms	bHLHe5; BMAL1; BMAL1c; JAP3; MOP3; PASD3; TIC
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Circadian rhythm - mammal

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