Mitofilin (IMMT) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, IHC, IP, WB
Recommend Dilution	Immunohistochemistry-Paraffin: 1:200-1:500, Immunohistochemistry: 1:200-1:500, Immunocytochemistry/ Immunofluorescence: 1:500, Immunoprecipitation, Western Blot: 1:2000
Reactivity	Human, Rat, Dog, Feline, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Whole human recombinant protein.
Formulation	0.05% sodium azide
Purification	Whole antisera
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	inner membrane mitochondrial protein
Database Link	NP_006830 Entrez Gene 76614 MouseEntrez Gene 312444 RatEntrez Gene 475764 DogEntrez Gene 10989 Human UniProt ID Q16891
Background	Mitochondria are the center of cellular energy production and essential metabolic reactions. As double membrane-bound organelles, mitochondria from different species, tissues, and metabolic states are highly polymorphic in nature, yet exhibit common structural features. The ultrastructural variations in mitochondrial architecture occur mainly due to the differences in the amount and shape of cristae. Abundant cristae are found in mitochondria from tissues where energy demand is high. Analysis of the human heart mitochondrial proteome shows that mitofilin is one of the most abundant mitochondrial proteins. It appears to play an important role in the maintenance of cristae morphology. Mitofilin was originally described as heart muscle protein (HMP) because of its high expression in the heart.
Synonyms	89; HMP; Mic60; MINOS2; P87; P89; PIG4; PIG52
Reference Data

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