FOXP3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1: 1000-5000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide made to the N-terminal region of human FOXP3 (between residues 1-50).
Formulation	Tris-citrate/phosphate, pH 7-8, 0.1% sodium Azide
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	forkhead box P3
Database Link	NP_054728 Entrez Gene 20371 MouseEntrez Gene 50943 Human UniProt ID Q9BZS1
Background	FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
Synonyms	AIID; DIETER; IPEX; JM2; PIDX; XPID
Reference Data
Protein Families	Transcription Factors

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