XRCC3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IP, WB
Recommend Dilution	Immunoprecipitation, Western Blot: 1:5000, ICC/IF (Negative)
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic partial peptide of human XRCC3.
Formulation	PBS and 0.05% sodium azide
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	X-ray repair complementing defective repair in Chinese hamster cells 3
Database Link	NP_005423 Entrez Gene 7517 Human UniProt ID O43542
Background	Five human RAD51 homologs have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homolgs interacts with one or more of the others, with all of the proteins involved in one complex or multiple smaller complexes. XRCC3 (x-ray cross complementing) was first identified as a human gene complementing the DNA damage sensitivity, chromosonal instability and impaired growth of the mutant hamster cell line irs1SF. This fact coupled with XRCC3 being a member of the RAD51 gene family have implied a role in the repair of DNA damage by homologous recombination.
Synonyms	CMM6
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Homologous recombination

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