BMAL1 (ARNTL) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ChIP, FC, ICC/IF, IHC, WB
Recommend Dilution	Chromatin Immunoprecipitation (ChIP), Knockout Validated, Flow Cytometry, Immunocytochemistry/ Immunofluorescence: 1:100, Flow (Intracellular), Immunohistochemistry-Paraffin: 1:250, Western Blot: 0.5 ug/mL - 2 ug/mL, Immunohistochemistry-Frozen, Immunohistochemistry: 1:250
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Bacterially expressed human MOP3 (C-terminus).
Formulation	Tris-citrate/phosphate buffer, pH 7-8 and 0.1% sodium azide
Concentration	lot specific
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	aryl hydrocarbon receptor nuclear translocator like
Database Link	NP_001169 Entrez Gene 406 Human UniProt ID O00327
Background	MOP3 (BMAL1), a general dimerization partner for a subset of the bHLH-PAS (basic-helix-loop-helix-PER-ARNT-SIM) superfamily of transcription regulators, is involved in circadian rhythm generation. MOP3 interacts with MOP4, CLOCK, hypoxia-inducible factor-1 alpha and -2 alpha. This interaction appears to be distinct from that of the more characterized general partner, ARNT (HIF-1Beta).
Synonyms	bHLHe5; BMAL1; BMAL1c; JAP3; MOP3; PASD3; TIC
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Circadian rhythm - mammal

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