FE65 (APBB1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IP, WB
Recommend Dilution	Immunoprecipitation: 2-10 ug, Western Blot: 1:1000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant rat protein expressed in bacteria.
Formulation	PBS, 15% glycerol and 0.02% sodium azide
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	amyloid beta precursor protein binding family B member 1
Database Link	NP_001155 Entrez Gene 11785 MouseEntrez Gene 29722 RatEntrez Gene 322 Human UniProt ID O00213
Background	FE65 is a signaling adaptor of APP protein. The FE65/APP complex was shown to translocate into the cell nucleus and regulate gene expression. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the complex in abnormal signaling detected in brains of Alzheimer Disease patients.
Synonyms	FE65; MGC:9072; RIR
Reference Data
Protein Families	Transcription Factors
Protein Pathways	Alzheimer's disease

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