Aromatase (CYP19A1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, IHC, Simple Western, WB
Recommend Dilution	Immunocytochemistry/ Immunofluorescence: 1:100, Western Blot: 1 ug/ml, Immunohistochemistry: 1:200, Simple Western, Immunohistochemistry-Paraffin: 1:200
Reactivity	Human, Monkey
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide made to a C-terminal portion of the human aromatase protein sequence (between residues 400-502).
Formulation	Tris-citrate / phosphate [pH 7-8] and 0.1% sodium azide
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	cytochrome P450 family 19 subfamily A member 1
Database Link	NP_000094 Entrez Gene 678697 MonkeyEntrez Gene 1588 Human UniProt ID P11511
Background	Aromatase is a key enzyme in steroidogenesis and plays an important role in sexual differentiation, fertility, and carcinogenesis. Many environmental chemicals may influence aromatase activity and thereby disrupt endocrine function.
Synonyms	ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM
Reference Data
Protein Families	Druggable Genome, P450
Protein Pathways	Androgen and estrogen metabolism, Metabolic pathways

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