SNVsMgp1 Rabbit Polyclonal Antibody
CAT#: TA160113
Rabbit Polyclonal Anti-Sin Nombre Virus Glycoprotein 2 Antibody
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CNY 5,808.00
货期*
4周
规格
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Specifications
Product Data | |
Recommend Dilution | ELISA: 1 ug/mL |
Reactivity | Sin Nombre orthohantavirus |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Sin Nombre virus glycoprotein 2 antibody was raised against a 16 amino acid peptide near the center of the Sin Nombre virus glycoprotein. |
Formulation | PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Background | Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins G1 (Gn) and G2 (Gc). While the G1 glycoprotein is is thought to be degraded by the host autophagy machinery, and this autophagic clearance is required for efficient virus repliaction (2), no such degradation was observed for the G2 glycoprotein. |
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