HTRA2 Mouse Monoclonal Antibody [Clone ID: 1B3]

Specifications

Product Data
Clone Name	1B3
Applications	ELISA, WB
Recommend Dilution	ELISA. Western blot (1:500 - 1:2,000).
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human HtrA2/Omi (134-458 aa) purified from E. coli
Specificity	The antibody recognizes human and mouse HtrA2/Omi. Does not react with rat. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	HtrA serine peptidase 2
Database Link	Entrez Gene 27429 Human UniProt ID O43464
Background	HtrA2/Omi is a mammalian serine protease at high temperatures and a chaperone at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Recently, HtrA2 has been known to contribute both to caspase-dependent and caspase-independent cell death.
Synonyms	OMI, Serine protease 25
Reference Data

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