MHC Class I (monomorphic) Mouse Monoclonal Antibody [Clone ID: CVS22]

Specifications

Product Data
Clone Name	CVS22
Applications	FC
Recommend Dilution	Flow cytometry: Neat-1/10, use 10µl of this working dilution to label 10e6 cells in 100µl.
Reactivity	Equine
Host	Mouse
Clonality	Monoclonal
Immunogen	Equine leucocytes
Specificity	All tissues
Formulation	PBS containing 0.09% Sodium azide and 1% BSA Label: FITC State: Purified State: Liquid purified IgG Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	FITC
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Background	MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.
Synonyms	MHC Class 1, HLA Class 1
Reference Data

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