CD4 Mouse Monoclonal Antibody [Clone ID: CC8]

Specifications

Product Data
Clone Name	CC8
Applications	FC
Recommend Dilution	Flow Cytometry.
Reactivity	Bovine
Host	Mouse
Clonality	Monoclonal
Immunogen	Spleen cells from an immunised mouse were fused with cells of the mouse NS1 myeloma cell line.
Specificity	CC8 precipitates a molecule of approximately 50kD and is considered to be the bovine homologue of Human CD4. The phenotype, tissue distribution and function of T-cells expressing the bovine CD4 antigen are similar to those in other species. However, expression on macrophages has not yet been detected.
Formulation	PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin Label: FITC State: Liquid purified IgG Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Database Link	Entrez Gene 407098 Bovine UniProt ID A7YY52
Background	CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
Synonyms	T-cell surface antigen T4/Leu-3
Reference Data

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