CD99 (CD99R Isoform) Mouse Monoclonal Antibody [Clone ID: MEM-131]

Specifications

Product Data
Clone Name	MEM-131
Applications	FC, IP, WB
Recommend Dilution	Flow Cytometry. Immunoprecipitation. Western Blotting under non reducing conditions. Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/ml, Positive tissue: thymic lymphocytes
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	HPB-ALL human peripheral blood leukemia T-cell line
Specificity	The antibody reacts with CD99R, an epitope restricted to a subset of CD99 molecule expressed on myeloid cells, NK cells and T lymphocytes.
Formulation	Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Precipitation methods; purity: > 95% (by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store the antibody at 2 - 8 °C. Do not freeze.
Gene Name	CD99 molecule
Database Link	Entrez Gene 4267 Human UniProt ID P14209
Background	CD99 (E2, MIC2) is a transmembrane glycoprotein that is involved in regulation of T cell addhesive properties and programmed cell death distinct from typical apoptosis course. CD99 roles are specific to certain stages of T cell differentiation such as corticothymocytes. CD99R isoform expression is restricted in the haematopoietic system to T, NK and myeloid cells.
Synonyms	E2 antigen, 12E7, MIC2X, MIC2Y
Reference Data

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