Blood Group A Antigen Mouse Monoclonal Antibody [Clone ID: HE-193]

Specifications

Product Data
Clone Name	HE-193
Applications	AGG, IHC
Recommend Dilution	Agglutination. Immunohistochemistry on Paraffin Sections.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with Blood Group A.
Specificity	This antibody recognizes Human Blood Group A (Monofucosyl and Difucosyl A antigens with chain types 1 and 2, A antigens with chain types 3, 4, 5, 6) and Forssman antigen.
Formulation	State: Supernatant State: Liquid Hybridoma Culture Supernatant 4 x concentrated by Ultrafiltration using 100 kDa-cut off membrane.
Conjugation	Unconjugated
Storage Condition	Store the antibody at 2-8°C. DO NOT FREEZE!
Background	Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens. Human blood group A antigen belongs to a group of carbohydrate determinats carried on both glycolipids and glycoproteins; it is detected on erythrocytes and certain epithelial cells.
Synonyms	Blood Group A Antigen
Reference Data

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