Pecam1 Mouse Monoclonal Antibody [Clone ID: TLD-3A12]

Specifications

Product Data
Clone Name	TLD-3A12
Applications	FC
Recommend Dilution	Flow Cytometry.
Reactivity	Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Activated, Lewis rat derived microglial cells.
Specificity	This antibody recognises PECAM-1 (CD31), a type 1 transmembrane protein expressed primarily on endothelial cells, platelets and leucocytes. Clone TLD-3A12 has been shown to partially block the proliferative response of antigen-specific CD4+ T cells to antigen-presenting cells and relevant antigen (3). We recommend the use of SM272LE for use in Functional Studies.
Formulation	PBS containing 1% BSA, 5% Sucrose and 0.09% Sodium Azide Label: PE State: Lyophilized purified IgG fraction Label: R. Phycoerythrin (RPE)
Reconstitution Method	Restore with 1 ml distilled water
Purification	Affinity Chromatography on Protein G
Conjugation	PE
Storage Condition	Prior to and following reconstitution store undiluted at 2-8°C. DO NOT FREEZE! This antibody should be protected from light as the PE-labelled product is photosensitive.
Gene Name	platelet and endothelial cell adhesion molecule 1
Database Link	Entrez Gene 29583 Rat UniProt ID Q3SWT0
Background	CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).
Synonyms	PECAM-1, EndoCAM, GPIIA'
Reference Data

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