Itgam Mouse Monoclonal Antibody [Clone ID: WT.3]
CAT#: SM264F
Itgam mouse monoclonal antibody, clone WT.3, FITC
Conjugation: Unconjugated Biotin
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CNY 5,489.00
Cited in 1 publication. |
Specifications
Product Data | |
Clone Name | WT.3 |
Applications | FC |
Recommend Dilution | Flow Cytometry: Use 10 µl of neat antibody to label 106 cells in 100 µl. |
Reactivity | Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | FTL-43. Lymph node cells from immunised BALB/c mice were fused with cells from the PAI mouse myeloma cell line. |
Specificity | Clone WT.3 reacts with the rat beta 2 integrin, which is designated CD18. The beta 2 integrin may be associated with the integrin alphaL, alphaX or alphaM subunits. The antibody has been shown to inhibit homotypic aggregation of PHA blasts. It also blocks binding of rat lymphocytes to purified rat ICAM-1. |
Formulation | PBS containing 0.09% Sodium Azide and 1% Bovine Serum Albumin Label: FITC State: Liquid purified IgG fraction Label: Fluorescein Isothiocyanate Isomer 1 |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | FITC |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. |
Gene Name | integrin subunit alpha M |
Database Link | |
Background | CD18 is an integrin. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA1, and combines with the alpha M chain to form the integrin Mac1. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling. CD18 is expressed by most leucocytes. Defects in the CD18 gene result in leukocyte adhesion deficiency. |
Synonyms | Integrin beta-2, MFI7 |
Reference Data |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Characteristics of Tendon Derived Stem Cells According to Different Factors to Induce the Tendinopathy
,Kim SJ, Song DH, Kim SJ,
J. Cell. Physiol.
,PubMed ID 29341108
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