Lag3 Rat Monoclonal Antibody [Clone ID: C9B7W]

CAT#: SM2270P

Lag3 rat monoclonal antibody, clone C9B7W, Purified

Size: 100 ug 250 ug



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CNY 6,116.00


货期*
4周

规格
    • 250 ug

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Specifications

Product Data
Clone Name C9B7W
Applications FC
Recommend Dilution Flow Cytometry: 1/50 - 1/200; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
Reactivity Mouse
Host Rat
Clonality Monoclonal
Immunogen Murine CD223 Ig fusion protein. Cells from immunised Lewis rats were fused with cells of the Sp/20 myeloma cell line.
Specificity This antibody recognises lymphocyte activation gene-3 (LAG-3)that is also referred to as CD223. Clone C9B7W recognises an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II. We recommend the use of SM2268LE for this purpose.
Formulation PBS, pH7.4 containing 0.09% Sodium Azide
State: Purified
State: Liquid purified IgG
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name lymphocyte-activation gene 3
Background CD223 is a 70kD activation-induced cell surface molecule. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion.
Synonyms LAG-3, FDC
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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