CD244 Mouse Monoclonal Antibody [Clone ID: 2B4.69]

Specifications

Product Data
Clone Name	2B4.69
Applications	FC, IP
Recommend Dilution	Flow Cytometry: 1/50 - 1/200; use 10 µl of the suggested working dilution to label 106 cells in 100 µl. Immunoprecipitation.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	CD244 Fusion protein. Spleen cells fron immunised Balb/c mice were fused with cells of the NS-1 myeloma cell line.
Specificity	This antibody is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKR2B4).
Formulation	PBS, pH7.4 State: Low Endotoxin State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	CD244 molecule
Database Link	Entrez Gene 51744 Human UniProt ID Q9BZW8
Background	The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells. CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.
Synonyms	NK cell type I receptor protein 2B4, NAIL, NKR2B4
Reference Data

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