MADCAM1 Mouse Monoclonal Antibody [Clone ID: 17F5]

CAT#: SM2238P

MADCAM1 mouse monoclonal antibody, clone 17F5, Purified



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CNY 6,116.00


货期*
4周

规格
    • 200 ug

Product images

Specifications

Product Data
Clone Name 17F5
Applications ELISA, IHC, WB
Recommend Dilution ELISA.
Western Blot (Non-Reducing Conditions). Detects a band of approximately 60kDa.
Immunohistochemistry on Paraffin Embedded Sections: 1/50-1/100. This product does not require protein digestion prior to staining. This product does not require HIER prior to staining.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant soluble MAdCAM-1-fc fusion protein.
Spleen cells from immunised Balb/c mice were fused with cells of the mouse P3X63Ag8.653 myeloma cell line.
Specificity This antibody recognizes Mucosal Addressin Cell Adhesion Molecule 1 (MAdCAM-1).
Clone 17F5 recognizes the Mucin domain of MAdCAM-1.
This antibody does not block the function of MAdCAM-1 (Leung, E. et al. 2004).
Formulation PBS
State: Purified
State: Liquid purified IgG fraction from Tissue Culture Supernatant
Preservative: 0.09% Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name mucosal vascular addressin cell adhesion molecule 1
Background Mucosal Addressin Cell Adhesion Molecule 1 (MAdCAM-1) is a 60kD transmembrane protein that belongs to the immunoglobulin superfamily. MAdCAM-1 is strongly expressed on mucosal lymphoid tissue and high endothelial venules of Peyers patches. Human MAdCAM-1 interacts with the beta 7 integrin LPAM-1 (alpha4beta7), CD62L, and VLA-4 (alpha4beta1) and is involved in lymphocyte trafficking.
Synonyms hMAdCAM-1, MAdCAM-1, Mucosal addressin cell adhesion molecule 1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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