Cd200r1 Rat Monoclonal Antibody [Clone ID: OX-110]

Specifications

Product Data
Clone Name	OX-110
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of neat antibody to label 106 cells in 100 µl. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors. This may be reduced by appropriate blocking. Clone OX-110 has been used successfully for the immunohistochemical detection of CD200R expressing cells on acetone fixed cryosections of murine synovial tissue (Simelyte et al. 2008).
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	Fusion protein mCD200RCD4d3+4.
Specificity	This antibody recognises CD200R.
Formulation	PBS containing 0.09% Sodium Azide, 5% Sucrose and 1% Bovine Serum Albumin Label: PE State: Lyophilized purified IgG fraction. Label: R. Phycoerythrin (RPE) Fluorophore        Excitation (nm) Emission (nm) PE 488nm laser   496                  578 PE 561nm laser   546                  578
Reconstitution Method	Restore with 1 ml distilled water
Concentration	lot specific
Purification	Affinity Chromatography on Protein G.
Conjugation	PE
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	CD200 receptor 1
Database Link	Entrez Gene 57781 Mouse UniProt ID Q9ES57
Background	CD200R is a cell surface glycoprotein (also known as OX2R). Mouse CD200R is a 326 amino acid, ~48 kDa single pass type I transmembrane glycoprotein, expressed primarily by peripheral blood monocytes and neutrophils but also by other leucocytes including T-lymphocytes and mast cells (Wright et al.2003). Studies suggest that CD200-CD200R interaction may be involved in the control of myeloid cellular function (Minas and Liversidge 2006).
Synonyms	CD200R1, CRTR2, MOX2R, OX2R, CD200 Receptor 1
Reference Data

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