LAIR1 Mouse Monoclonal Antibody [Clone ID: NKTA255]

Specifications

Product Data
Clone Name	NKTA255
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells in 100 µl.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	NK cells lines B12.100 and AM.25.
Specificity	This antibody recognizes leukocyte-associated Ig-like receptor-1 (LAIR-1). Clone NKTA255 is reported to inhibit NK cell triggering via CD16 molecules (Ref.3)
Formulation	PBS, pH 7.4 containing 0.09% Sodium Azide and 1% BSA Label: FITC State: Liquid purified IgG fraction Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	FITC
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	leukocyte associated immunoglobulin like receptor 1
Database Link	Entrez Gene 3903 Human UniProt ID Q6GTX8
Background	LAIR-1 is a 40kD cell surface molecule that functions as an inhibitory receptor on natural killer cells, monocytes and T cells. LAIR-1, otherwise known as CD305, is also expressed by other haematopoeitic cells including B cells, but is not expressed by nonhaematopoietic, platelets or erythrocytes.
Synonyms	LAIR-1, hLAIR1
Reference Data

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