CD226 Mouse Monoclonal Antibody [Clone ID: DX11]
CAT#: SM2023P
CD226 mouse monoclonal antibody, clone DX11, Aff - Purified
Size: 100 ug
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CNY 6,116.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | DX11 |
Applications | FC, IP |
Recommend Dilution | Flow Cytometry: 1/50 - 1/200; Use 10µl of the suggested working dilution to label 1 x 10e6 cells in 100µl. Immunoprecipitation. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human cytotoxic T lymphocyte clone. Spleen cells from immunised BALB/c mouse were fused with cells of the Sp2/0 myeloma cell line. |
Specificity | This antibody recognises CD226. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells. We recommend the use of SM2023A for funtional studies. |
Formulation | PBS, pH7.4 containing 0.09% Sodium Azide State: Aff - Purified State: Liquid purified IgG |
Concentration | lot specific |
Purification | Affinity chromatography on Protein G |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | CD226 molecule |
Database Link | |
Background | CD226 is a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. |
Synonyms | DNAX accessory molecule 1, DNAM-1 |
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