CD46 Mouse Monoclonal Antibody [Clone ID: MEM-258]

Specifications

Product Data
Clone Name	MEM-258
Applications	FC
Recommend Dilution	Flow cytometry: use 10 µl of neat antibody to label 10e6 cells.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	HPB-ALL cell line
Specificity	This antibody recognises the human CD46 cell surface antigen, a broadly expresed glycoprotein also known as membrane co-factor protein (MCP).
Formulation	PBS with 0.09% sodium azide as preservative and 1% BSA as stabilizer Label: PE State: Lyophilized purified immunoglobulin fraction Label: R. Phycoerythrin
Reconstitution Method	Restore with 1 ml distilled water.
Purification	Protein A affinity chromatography
Conjugation	PE
Storage Condition	Store at 2-8°C. This product should be stored undiluted. DO NOT FREEZE. This product is photosensitive and should be protected from light.
Gene Name	CD46 molecule
Database Link	Entrez Gene 4179 Human UniProt ID P15529
Background	CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilisation.
Synonyms	TLX, MIC10
Reference Data

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