CD46 Mouse Monoclonal Antibody [Clone ID: MEM-258]

Specifications

Product Data
Clone Name	MEM-258
Applications	FC, IP, WB
Recommend Dilution	Flow cytometry: 1/10 - 1/50; use 10 µl of the suggested working dilution to label 10e6 cells. Immunoprecipitation. Western Blot.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	HPB-ALL cell line
Specificity	This antibody recognises the CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP).
Formulation	PBS containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD46 molecule
Database Link	Entrez Gene 4179 Human UniProt ID P15529
Background	CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilisation.
Synonyms	TLX, MIC10
Reference Data

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