Il6 Rat Monoclonal Antibody [Clone ID: MP5-32C11]
CAT#: SM1695A
Il6 rat monoclonal antibody, clone MP5-32C11, Azide Free
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CNY 4,077.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | MP5-32C11 |
Applications | ELISA, FN, IP, WB |
Recommend Dilution | Functional assays. Immunoassays. Immunoprecipitation. Western blot: The typical starting working dilution is 1:10. The antibody can be used for immunochemical investigations of mouse IL-6 in structural studies and for quantitative/qualitative immunochemical detection methods. The antibody neutralizes the biological activity of mouse IL-6. Furthermore the antibody is useful for Western blot and as tracer antibody use in immuno assay procedures. |
Reactivity | Mouse |
Host | Rat |
Clonality | Monoclonal |
Specificity | The antibody neutralizes mouse interleukin 6 (IL-6). It does not cross-react with LPS (the component of the bacterial cell wall which is considered responsible for the toxicity of gram-negative bacteria) and TNF-alpha nor does it block human or rat IL-6 in proliferation assays using the KD83 cell line. MP5-32C11 inhibits mouse IL-6-induced proliferation of the NFS60 myelomonocytic cell line and KD83 plasmacytoma. |
Formulation | PBS State: Azide Free State: Lyophilized Ig fraction |
Reconstitution Method | Reconstitute the vial by injection of 0.5 ml sterile distilled or de-ionised water (Caution: vial is under vacuum). |
Purification | Protein G |
Conjugation | Unconjugated |
Storage Condition | Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Gene Name | interleukin 6 |
Database Link | |
Background | IL-6 is a pluripotent 20-22 kDa cytokine which plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and haematopoiesis. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. Continuous IL-6 gene expression makes an essential contribution to a multistep oncogenesis of plasma cell neoplasia. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas. |
Synonyms | IL-6, Interferon beta-2, IFNB2, B-cell stimulatory factor 2, BSF-2, CDF |
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