CD19 Mouse Monoclonal Antibody [Clone ID: LT19]
CAT#: SM1529PP
CD19 mouse monoclonal antibody, clone LT19, PerCP
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CNY 4,340.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | LT19 |
Applications | FC |
Recommend Dilution | Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Daudi human Burkitt lymphoma cell line |
Specificity | This antibody reacts with CD19 (B4), a 95 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on B lymphocytes and follicular dendritic cells; it is lost on plasma cells. |
Formulation | Phosphate buffered saline (PBS) Label: PerCP State: Liquid purified Ig fraction Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) Preservative: 15 mM sodium azide |
Conjugation | PerCP |
Storage Condition | Store undiluted at 2-8°C. DO NOT FREEZE! This products is photosensitive and should be protected from light. |
Gene Name | CD19 molecule |
Database Link | |
Background | CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity. |
Synonyms | Leu-12, B-cell marker |
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