KIR2DL3 Mouse Monoclonal Antibody [Clone ID: GL183]

Specifications

Product Data
Clone Name	GL183
Applications	FC, IP, WB
Recommend Dilution	Flow cytometry: 1/10 - 1/50; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl. Immunoprecipitation.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	NK cell clone E57. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3UI myeloma cell line.
Specificity	This antibody recognises the CD158b cell surface antigen. This antibody also recognises a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail.
Formulation	PBS containing 0.09% Sodium Azide and 0.1% Bovine Serum Albumin State: Purified State: Liquid purified IgG
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
Database Link	Entrez Gene 3804 Human UniProt ID P43628
Background	CD158b is a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). The antigen is a members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.
Synonyms	KIRCL23
Reference Data

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