CD71 (TFRC) Mouse Monoclonal Antibody [Clone ID: DF1513]

Specifications

Product Data
Clone Name	DF1513
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of neat antibody to label 1x10e6 cells.
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	KGI cell line. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Specificity	This antibody recognises the human CD71 cell surface antigen, a 190 kD homodimeric glycoprotein expressed by proliferating cells. CD71 acts as receptor for transferrin.
Formulation	PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 0.1% BSA as stabilizer. Label: PE State: Lyphilized purified IgG fraction. Label: R-Phycoerythrin
Reconstitution Method	Restore with 0.25 ml distilled water.
Concentration	lot specific
Purification	Affinity Chromatography on Protein G.
Conjugation	PE
Storage Condition	Prior to and following reconstitution store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	transferrin receptor
Database Link	Entrez Gene 7037 Human UniProt ID P02786
Background	The transferrin receptor has been structurally characterized as a sulfide bound dimer of identical glycoprotein subunits of 95 kDa. The transferrin receptor is not present on resting blood lymphocytes. On PBL, the receptor appears after activation. The expression of transferrin receptor is coordinately regulated with cell growth. Present on T and B cell lines. The soluble (or serum) transferrin receptor (sTfR) is a circulating truncated form of the membrane receptor protein; it is an 85 kDa glycoprotein forming in serum a 320 kDa complex with diferric transferrin. The most important clinical use of the sTfR determination is in the differential diagnosis between iron deficiency anaemia and the anaemia of chronic disease.
Synonyms	TfR1, p90, Transferrin receptor protein 1
Reference Data

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