CD49b (ITGA2) Mouse Monoclonal Antibody [Clone ID: AK7]

CAT#: SM1125PS

CD49b (ITGA2) mouse monoclonal antibody, clone AK7, Purified

Size: 100 ug 200 ug



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CNY 4,499.00


货期*
4周

规格
    • 100 ug

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Specifications

Product Data
Clone Name AK7
Applications FC
Recommend Dilution Flow Cytometry: Use 10 µl of 1/50-1/100 diluted antibody to label 10e6 cells in 100 µl.
Immunohistochemistry on Frozen Sections: 1/500-1/1000.
Recommended Positive Control Tissue: Tonsil.
Reactivity Human, Monkey
Host Mouse
Clonality Monoclonal
Immunogen Spleen cells from immunised mice were fused with cells of the mouse NS1 myeloma cell line.
Specificity This antibody recognises the integrin alpha 2 subunit, which is 160kD cell surface antigen expressed by NK cells and a small subset of T-cells.
This antibody inhibits cell attachment to collagen.
Formulation PBS containing 0.09% Sodium Azide as preservative.
State: Purified
State: Liquid purified IgG fraction.
Concentration lot specific
Purification Affinity Chromatography on Protein G.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name integrin subunit alpha 2
Background Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.
Synonyms Integrin alpha-2, ITGA-2, VLA-2 alpha, VLA2, GPIa, Collagen Receptor
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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