CD44 Mouse Monoclonal Antibody [Clone ID: VFF-9]

Specifications

Product Data
Clone Name	VFF-9
Applications	FC, IHC, WB
Recommend Dilution	Flow cytometry: 1/50; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl. Western Blot. Immunohistochemistry on frozen sections: 1/50. Immunohistochemistry on paraffin sections: 1/50; This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Recommended Positive Control: Skin.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human CD44v7.
Specificity	This antibody specifically recognises an epitope encoded by exon v7 on the variant portion of CD44.
Formulation	PBS containing 0.01% Thimerosal State: Purified State: Liquid purified IgG
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD44 molecule (Indian blood group)
Database Link	Entrez Gene 960 Human UniProt ID P16070
Background	CD44 is a receptor for hyaluronic acid (HA). It mediates cell to cell and cell matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix matalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post translational modification events.
Synonyms	CD44, LHR, MDU2, MDU3, MIC4, Phagocytic glycoprotein I, PGP-1, HUTCH-I, Extracellular matrix receptor-III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican, CDw44
Reference Data

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