CD48 Mouse Monoclonal Antibody [Clone ID: MEM-102]

Specifications

Product Data
Clone Name	MEM-102
Applications	FC, IHC, IP, WB
Recommend Dilution	Flow cytometry (2 µg/ml). Immunoprecipitation. Western blot. Immunohistochemistry (paraffin sections).
Reactivity	Human, Primate
Host	Mouse
Clonality	Monoclonal
Immunogen	Raji human Burkitt's lymphoma cell line
Specificity	The antibody reacts with CD48 antigen (Blast-1), a 40-47 kDa GPI-anchored membrane protein (immunoglobulin supergene family) widely expressed on hematopoietic cells; it is negative on granulocytes, platelets and erythrocytes.
Formulation	Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein-A affinity chromatography; purity: > 95% (by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	CD48 molecule
Database Link	Entrez Gene 962 Human UniProt ID P09326
Background	CD48 (Blast-1) belongs to the CD2 subset of the Ig superfamily, which includes CD2, CD2F-10, CD58, CD84, CD150, CD229, CD244 and others. These molecules bind to the same or another members of their family, thus mediate homotypic or heterotypic adhesion. CD48 is a GPI-anchored protein broadly expressed on hematopoietic cells and serves as a high affinity ligand for 2B4 and low affinity ligand for CD2. 2B4-CD48 interaction among NK cells and NK-T cells regulates cell proliferation. Signaling through CD48 results in eosinophil activation and CD48 expression is increased in several infectious diseases.
Synonyms	BCM1, BLAST1, MEM-102, TCT.1
Reference Data

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