CD48 Mouse Monoclonal Antibody [Clone ID: MEM-102]

Specifications

Product Data
Clone Name	MEM-102
Applications	FC, IHC, IP, WB
Recommend Dilution	Flow Cytometry. Western Blot. Immunohistochemistry on frozen sections: 1/50 - 1/100 Immunohistochemistry on paraffin sections: This product does not require protein digestion pre-treatment of paraffin sections; This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Recommended Positive Control Tissue: Tonsil.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognises to the 45kD leucocyte surface glycoprotein specific for the CD48 antigen which is closely related to the activation antigen, Blast-1. It is useful in the detection of CD48 positive cells and may be used in studies to differentiate haemapoietic tumours, sarcomas and melanomas.
Formulation	PBS, pH7.4 containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD48 molecule
Database Link	Entrez Gene 962 Human UniProt ID P09326
Background	CD48 is a glycosyl phophatidyl inositol (GPI) anchored cell surface protein also known as Blast1, HuLy m3, BCM1 (in mouse), and OX45 (in rat). CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibrolasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2. The CD48 antigen is closely related to the activation antigen, Blast 1.
Synonyms	BCM1, BLAST1, MEM-102, TCT.1
Reference Data

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