CD42a (GP9) Mouse Monoclonal Antibody [Clone ID: GRP-P]
CAT#: SM1104PS
CD42a (GP9) mouse monoclonal antibody, clone GRP-P, Purified
Size: 200 ug
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CNY 3,140.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | GRP-P |
Applications | FC |
Recommend Dilution | Flow Cytometry. |
Reactivity | Canine, Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human acute lymphoblastic leukemia cells |
Specificity | The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets. HLDA IV.; WS Code P 35. |
Formulation | PBS, pH~7.4 State: Purified State: Liquid purified IgG fraction from cell Culture Supernatant (> 95% pure by SDS-PAGE) Preservative: 15 mM Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein-A |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C. DO NOT FREEZE! |
Gene Name | glycoprotein IX platelet |
Database Link | |
Background | CD42a, also known as Glycoprotein 9 (GPIX), composes together with GPIb alpha, GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. |
Synonyms | Platelet glycoprotein IX, GP-IX, GP9 |
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