CD9 Mouse Monoclonal Antibody [Clone ID: MM2/57]

Specifications

Product Data
Clone Name	MM2/57
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10µl of Neat-1/5 diluted antibody to label 10e6 cells or 100µl whole blood.
Reactivity	Bovine, Canine, Equine, Feline, Human, Monkey, Porcine, Rabbit
Host	Mouse
Clonality	Monoclonal
Immunogen	Human platelet membrane. Spleen cells from BALB/c mice immunised were fused with cells of the mouse SP2/0 myeloma line.
Specificity	This antibody recognises CD9, a 24kD surface glycoprotein expressed by platelets, monocytes, some lymphocytes and endothelial cells.
Formulation	Contains 0.09% Sodium Azide as preservative and 1% Bovine Serum Albumin as stabilizer. Label: Biotin State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Biotin
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD9 molecule
Database Link	Entrez Gene 928 Human UniProt ID P21926
Background	CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve.
Synonyms	MIC3, TSPAN29, GIG2, p24, Tetraspanin-29, 5H9 antigen
Reference Data

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