Ifng Mouse Monoclonal Antibody [Clone ID: DB1]

Specifications

Product Data
Clone Name	DB1
Applications	ELISA, IHC
Recommend Dilution	ELISA: 10µg/ml - 100µg/ml. Immunohistochemistry on frozen sections.
Reactivity	Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant rat IFN gamma.
Specificity	This antibody reacts with IFN-gamma. Clone DB-1 exhibits high affinity binding to the natural and recombinant forms and effectively neutralises the anti viral activity of IFN-gamma. It also blocks the induction of Ia antigen expression on murine keratinocytes. There is no cross-reaction with rodent IFN-alpha or IFN-beta or with human interferons. Clone DB-1 has also been reported for use in neutralising studies. MCA1301XZ is recommended for this purpose.
Formulation	PBS containing 125mM trehalose and 0.09% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	interferon gamma
Database Link	Entrez Gene 15978 Mouse UniProt ID P01580
Background	Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2.
Synonyms	IFN-gamma, gamma IFN
Reference Data

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