Macrophages / Monocytes Rat Monoclonal Antibody [Clone ID: MOMA-2]

Specifications

Product Data
Clone Name	MOMA-2
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of neat-1/10 diluted antibody to label 106 cells in 100 µl (Membrane permeabilisation is recommended).
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	Mouse lymph node stroma.
Specificity	The antibody recognizes an intracellular antigen of Mouse Macrophages and Monocytes. It reacts strongly with Macrophages in lymphoid organs such as tingible body Macrophages and Macrophages in T cell dependent areas. Reacts on all Mouse strains tested.
Formulation	PBS Label: FITC State: Liquid purified IgG fraction Stabilizer: 1% BSA Preservative: 0.09% Sodium Azide Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	FITC
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Background	Monocyte and macrophage are white blood cells that roam the body tissues engulfing foreign organisms. A monocyte is a leukocyte, part of the human body's immune system that protects against blood-borne pathogens and moves quickly (aprox. 8-12 hours) to sites of infection in the tissues. Monocytes are usually identified in stained smears by their large bi-lobed nucleus. Macrophages are cells within the tissues that originate from specific white blood cells called monocytes. Monocytes and macrophages are phagocytes, acting in both nonspecific defense (or innate immunity) as well as specific defense (or cell-mediated immunity) of vertebrate animals. Their role is to phagocytize (engulf and then digest) cellular debris and pathogens either as stationary or mobile cells, and to stimulate lymphocytes and other immune cells to respond to the pathogen.
Synonyms	Macrophage marker, Monocyte marker
Reference Data

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