TACI (TNFRSF13B) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Neutralization. Sandwich ELISA: To detect Human TACI by Sandwich ELISA (using 100 µl/well antibody solution) a concentration of 0.5-2.0 µg/ml of this antibody is required. This anitbody in conjunction with biotinylated anti-Human TACI (PP1218B1 and PP1218B2), allows the detection of at least 0.2-0.4 ng/well of recombinant Human TACI. Western Blot: To detect Human TACI by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant Human TACI is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	E. Coli derived recombinant Human TACI.
Formulation	PBS, pH 7.2 without preservatives. State: Aff - Purified State: Lyophilized (sterile filtered) purified Ig fraction.
Reconstitution Method	Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/ml.
Purification	Affinity Chromatography employing immobilized Hman TACI matrix.
Conjugation	Unconjugated
Storage Condition	The lyophilized antibody is stable at room temperature for up to one month. The reconstituted solution can be stored at 2-8°C for at least two weeks. Frozen aliquots are stable for at least six months when stored at -20°C. Avoid repeated freezing and thawing.
Gene Name	tumor necrosis factor receptor superfamily member 13B
Database Link	Entrez Gene 23495 Human UniProt ID O14836
Background	TACI is a lymphocyte specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein binds to both APRIL and BAFF and induces activation of the transcription factors NFAT (nuclear-factor of activated T cells), AP1, and NF kappa B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith Magenis syndrome region on chromosome 17.
Synonyms	TNFRSF13B
Reference Data

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