Peptide YY / PYY Guinea Pig Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Immunofluorescence Microscopy: 1/1500-1/2500 using FITC with overnight incubation at 2-8°C. Immunohistochemistry on Frozen and Paraffin Sections. Recommended Positive Control: Frozen Sections of Rat intestine.
Reactivity	Feline, Human, Mouse, Rat
Host	Guinea Pig
Clonality	Polyclonal
Immunogen	Synthetic Porcine peptide YY (Peninsula).
Specificity	This antibody reacts with PYY (Peptide YY). Absorption with 10-100 µg immunogen per ml diluted antiserum abolishes the staining.
Formulation	State: Serum State: Lyophilized undiluted Serum
Reconstitution Method	Dissolve the antiserum in 100 µl distilled water
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Database Link	UniProt ID P68005
Background	The intestinal peptide YY is related to the PP-family of peptides and occurs in the glicentin cells in the gut. They are numerous in the rectum, colon, and ileum and few in the duodenum and jejunum. PYY has hormone-like action, inhibits gut motility and pancreatic exocrine secretion and cause vasoconstriction. PYY may occur in endorine tumors of the pancreas and of the rectum.
Synonyms	Peptide tyrosine tyrosine, PYY-I, Peptide YY(3-36), PYY-II
Reference Data

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