GLP1 (GCG) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Immunohistochemistry on frozen and paraffin sections: 1/2000-1/3000 (PAP); with overnight incubation at 2-8°C. Positive Control: Formalin-fixed paraffin sections of pig pancreas. Immunofluorescence: 1/1000-1/1500.
Reactivity	Human, Porcine, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Porcine pancreatic glucagon (Novo, Denmark), conjugated to BSA.
Specificity	This antibody reacts to Glucagon/Glicentin.
Formulation	State: Serum State: Lyopilized serum
Reconstitution Method	Dissolve the antiserum in 50-100 µl distilled water, and dilute further in 0.1 M PBS with 1% BSA and 0.09% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month  or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	glucagon
Database Link	Entrez Gene 2641 Human UniProt ID P01275
Background	Glicentin contains the glucagon sequence and is produced in a prominent population of endocrine cells in the distal intestine as well as in pancreatic glucagon cells and in the nerves in the brain. Serum levels of glicentin are elevated after food uptake and in certain clinical conditions, e.g. after resections of the intestine. The functional role of glicentin is largely unknown. Glicentin occurs in endocrine tumors arising in the distal intestine (rectal carcinoids) and in pancreatic islet cell tumors.
Synonyms	GCG
Reference Data

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