PROX1 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF
Recommend Dilution	Immunofluorescence: 1-5 µg/ml.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant highly conserved C-terminal part of the homeobox transcription factor Human Prox1 (homeo domain and prospero domain) (Cat.-No DA3565).
Specificity	This antibody will detect Prox-1 in the nucleus of lymphatic endothelial cells.
Formulation	5mM PBS, pH 7.2 Label: Biotin State: Lyophilized purified IgG fraction Stabilizer: 50X BSA Preservative: 0.02% Sodium Azide
Reconstitution Method	Restore in sterile water to a concentration of 0.1-1.0 mg/ml
Purification	Antigen Affinity Chromatography
Conjugation	Biotin
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	prospero homeobox 1
Database Link	Entrez Gene 19130 MouseEntrez Gene 305066 RatEntrez Gene 5629 Human UniProt ID Q92786
Background	Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells.
Synonyms	PROX1
Reference Data
Protein Families	Embryonic stem cells, ES Cell Differentiation/IPS

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