Cytokeratin 5 (KRT5) Mouse Monoclonal Antibody [Clone ID: XM26]

Specifications

Product Data
Clone Name	XM26
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Embedded Sections: 1/50-1/75 (ABC method), Incubation of 30 minutes at room temperature. We suggest an Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Skin.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Prokaryotic recombinant protein corresponding to 103 amino acid portion of C-terminal region of the Human Cytokeratin 5 molecule
Specificity	This antibody reacts with Cytokeratin 5 intermediate filament protein. Cellular Localization: Cytoplasmic.
Formulation	State: Supernatant State: Liquid Culture Supernatant Preservative: < 0.1% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	keratin 5
Database Link	Entrez Gene 3852 Human UniProt ID P13647
Background	Basal cells of human epidermis express acidic Cytokeratin 14 and basic Cytokeratin 5. Cytokeratin 5 is a 58 kD protein, which is closely related to Cytokeratin 6. Cytokeratin 5 and 6 are expressed in basal cell epithelioma, basal cells of prostate, urothelium, vagina, squamous cell carcinomas of skin, tongue, epiglottis and rectal-anal region. Cytokeratin 5 can be useful in the distinction of mesotheliomas from most adenocarcinomas.
Synonyms	KRT5, Cytokeratin-5, Keratin-5, Keratin 5, CK5, K5
Reference Data

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