CD34 Mouse Monoclonal Antibody [Clone ID: 34C02]

CAT#: DM3515P

CD34 mouse monoclonal antibody, clone 34C02, Purified



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CNY 3,100.00


货期*
5周

规格
    • 50 ug

Cited in 1 publication.

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Specifications

Product Data
Clone Name 34C02
Applications FC, IHC
Recommend Dilution Flow Cytometry.
Immunohistology on Frozen Sections.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant Human CD34 protein.
Specificity This antibody reacts with CD34 - expressed on lymphoid and myeloid hematopoietic progenitor cells.
Also reacts with vascular endothelial cells in normal tissues and in benign and malignant proliferations.
Formulation 10 mM PBS, pH 7.4 without preservatives or stabilizers
State: Purified
State: Lyophilized purified IgG fraction
Reconstitution Method Restore in sterile Water to a concentration of 1.0 mg/ml.
Purification Protein G Chromatography
Conjugation Unconjugated
Storage Condition Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Gene Name CD34 molecule
Background The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 have been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.
CD34, a single chain transmembrane glycoprotein, is selectively expressed on human lymphoid and myeloid hematopoietic progenitor cells.
Synonyms Hematopoietic progenitor cell marker
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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