VEGF Receptor 2 (KDR) Mouse Monoclonal Antibody [Clone ID: KDREWC]
CAT#: DM3503B
VEGF Receptor 2 (KDR) mouse monoclonal antibody, clone KDREWC, Biotin, Purified
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CNY 5,288.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | KDREWC |
Applications | ELISA, FC, WB |
Recommend Dilution | ELISA (1-10 µg/ml) FACS analysis and Cell Sorting (2-20 µg/ml). |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Recombinant Human soluble extracellular KDR protein (D7) (110 kDa) |
Specificity | The monoclonal antibody will detect native Human VEGFR-2/KDR in ELISA experiments and on the surface of different Human cell types. |
Formulation | PBS Label: Biotin State: Purified State: Lyophilized purified IgG fraction from Cell Culture Supernatant Stabilizer: 50xBSA Preservative: 0.02% Sodium Azide |
Reconstitution Method | Restore in distilled sterile water to 0.1-1.0 mg/ml |
Purification | Protein G Chromatography |
Conjugation | Biotin |
Storage Condition | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
Gene Name | kinase insert domain receptor |
Database Link | |
Background | Endothelial cells express three different vascular endothelial growth factor (VEGF) receptors, belonging to the family of receptor tyrosine kinases (RTKs). They are named VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk-1), VEGFR-3 (Flt-4). Their expression is almost exclusively restricted to endothelial cells, but VEGFR-1 can also be found on monocytes. All VEGF-receptors have seven immunoglobulin-like extracellular domains, a single transmembrane region and an intracellular split tyrosine kinase domain. VEGFR-2 has a lower affinity for VEGF than the Flt-1 receptor, but a higher signaling activity. Mitogenic activity in endothelial cells is mainly mediated by VEGFR-2 leading to their proliferation. The binding of VEGF165 to VEGFR-2 is dependent on heparin. |
Synonyms | VEGFR2, FLK1, KDR, VEGF Receptor 2 |
Reference Data |
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