MCP1 (CCL2) Mouse Monoclonal Antibody [Clone ID: S382]
CAT#: DM2030
MCP1 (CCL2) mouse monoclonal antibody, clone S382, Azide Free
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CNY 7,337.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | S382 |
Applications | ELISA, FN |
Recommend Dilution | ELISA: React with Human MCP-1. Neutralizing: Tests on the ability to inhibit monocyte chemotaxis toward 1 nM recombinant human MCP-1 in blindwell chambers showed that the antibodies were particularly effective on blocking MCP1 activity. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant Human MCP1. |
Specificity | This MCP1 antibody reacts with natural and recombinant Human MCP-1. Does not react with Human Interleukin-8 (IL-8) and other human cytokines tested such as interleukin-1 beta (IL1 beta), serum Amyloid A (SAA) and epidermal growth factor (EGF). |
Formulation | 0.01M PBS, pH 7.2 without preservatives. State: Azide Free State: Lyophilized purified IgG fraction. |
Reconstitution Method | Restore with double distillated water to adjust the final concentration to 1.00 mg/ml |
Purification | Affinity Chromatography on Protein G. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody at -20°C. Avoid repeated freezing and thawing. |
Gene Name | C-C motif chemokine ligand 2 |
Database Link | |
Background | This chemotactic factor attracts monocytes and basophils but not neutrophils or eosinophils and augments monocyte anti-tumor activity. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. It may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. |
Synonyms | C-C motif chemokine 2, SCYA2, MCAF, Small-inducible cytokine A2, MCP-1, HC11, HC-11 |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway |
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