GCSF Receptor (CSF3R) Mouse Monoclonal Antibody [Clone ID: S-1284]

Specifications

Product Data
Clone Name	S-1284
Applications	ELISA, WB
Recommend Dilution	ELISA. Immunoblotting: Recognizes denatured G-CSFR following SDS-PAGE and blotting of 200 µg of cell lysate or following immunoprecipitation with polyclonal antibody followed by immunoblotting. Western Blot: At an antibody concentration of 1-10 µg/mL will allow visualization of 250 ng/lane of human G-CSFR-MBP.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant MBP-GCSFR fusion protein
Specificity	This antibody detects G-CSFR (CD114). Does not cross-react with MBP or BSA (bovine serum albumin).
Formulation	0.01 M PBS, pH 7.2 State: Purified State: Lyophilized
Reconstitution Method	In double distilled water to a concentration to 1.00 mg/ml
Purification	Protein G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Gene Name	colony stimulating factor 3 receptor
Database Link	Entrez Gene 1441 Human UniProt ID Q99062
Background	The protein encoded by the GCSF Receptor gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, of which three are membrane-bound and the one secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.
Synonyms	G-CSF-R, GCSFR, GCSF Receptor, G-CSF Receptor
Reference Data

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