Ly75 Rat Monoclonal Antibody [Clone ID: NLDC-145]

CAT#: DDX0020A488-100

Ly75 rat monoclonal antibody, clone NLDC-145



Need it in bulk or conjugated?
Get a free quote

CNY 6,281.00


货期*
4周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name NLDC-145
Applications FC, IF
Recommend Dilution Flow Cytometry, IF
Reactivity Mouse
Host Rat
Clonality Monoclonal
Immunogen Mouse lymphoid tissue stroma
Specificity Mouse dendritic cells
Formulation PBS 50% glycerol
Label: Alexa Fluor 488
Concentration lot specific
Purification QMA Hyper D ion exchange chromatography
Conjugation Alexa Fluor 488
Storage Condition -20°C. KEEP CONTENTS STERILE: no preservative.
Purified antibodies: avoid repeated freeze/thaw cycles.
Coupled antibodies: glycerol protects from freezing.
Gene Name lymphocyte antigen 75
Background NLDC-145 has been described as reacting specifically with a group of nonlymphoid dendritic cells including Langerhans cells (LC), veiled cells (VC), and interdigitating cells (IDC). The antibody does not react with precursor cells in bone marrow and blood. Macrophages are not stained by the antibody, but a subpopulation of Ia+ peritoneal exudate cells is recognized. It stains DC in T lymphocyte areas, including spleen white pulp but not spleen marginal zone DC or LC. The Ag is also expressed on activated macrophages and thymic cortical epithelium. DEC-205 has some similarities with mannose receptors and acts as a receptor for Ag uptake. (Kraal G., et al, J.Exp.med. 1986, 163, 981 ; Steinman RM, et al, PNAS, 2002, 99, 351-358 ; Flores-Langarica et al, PNAS, 2005, 102, 19039-19044) ATCC ref: HB-290TM.
Synonyms LY75, CLEC13B, DEC205, gp200-MR6
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...