ICOS Mouse Monoclonal Antibody [Clone ID: OTI3E8]

Specifications

Product Data
Clone Name	OTI3E8
Applications	FC
Recommend Dilution	FLOW 1:100~400
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human ICOS (NP_036224) produced in 293F cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	20.2 kDa
Gene Name	inducible T cell costimulator
Database Link	NP_036224 Entrez Gene 29851 Human UniProt ID Q9Y6W8
Background	The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008]
Synonyms	AILIM; CD278; CVID1
Reference Data
Protein Families	Secreted Protein, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Primary immunodeficiency, T cell receptor signaling pathway

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