TNFSF9 Mouse Monoclonal Antibody [Clone ID: OTI15C9]
CAT#: CF813220
Carrier-free (BSA/glycerol-free) CD137L mouse monoclonal antibody,clone OTI15C9
Formulation: Standard
View other "OTI15C9" antibodies (4)
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CNY 3,999.00
Specifications
Product Data | |
Clone Name | OTI15C9 |
Applications | FC, WB |
Recommend Dilution | WB 1:1000, FLOW 1:100 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human CD137L (NP_003802) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 26.4 kDa |
Gene Name | TNF superfamily member 9 |
Database Link | |
Background | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. [provided by RefSeq, Oct 2008] |
Synonyms | 4-1BB-L; CD137L; TNLG5A |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA813220 | CD137L mouse monoclonal antibody,clone OTI15C9 |
CNY 1,999.00 |
|
TA813220AM | CD137L mouse monoclonal antibody,clone OTI15C9, Biotinylated |
CNY 3,990.00 |
|
TA813220BM | CD137L mouse monoclonal antibody,clone OTI15C9, HRP conjugated |
CNY 3,990.00 |
|
TA813220S | CD137L mouse monoclonal antibody,clone OTI15C9 |
CNY 800.00 |