Diazepam Binding Inhibitor (DBI) Mouse Monoclonal Antibody [Clone ID: OTI4A8]

Specifications

Product Data
Clone Name	OTI4A8
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 2-104 of human DBI (NP_065438) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	11.6 kDa
Gene Name	diazepam binding inhibitor, acyl-CoA binding protein
Database Link	NP_065438 Entrez Gene 1622 Human UniProt ID P07108
Background	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. [UniProtKB/Swiss-Prot Function]
Synonyms	ACBD1; ACBP; CCK-RP; EP
Reference Data
Protein Families	Druggable Genome
Protein Pathways	PPAR signaling pathway

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